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School of Biotechnology and Food Engineering Made Major Headway in Gene Expression Regulation of Tomato Nutrients
time: Jan 23, 2016

New Phytologist, a leading world journal, published Ubiquitin-conjugated degradation of golden 2-like transcription factor is mediated by CUL4-DDB1-based E3 ligase complex in tomato online on September 11, 2015. This is a major progress made by Professor Liu Yongsheng’s research team. http://onlinelibrary.wiley.com/doi/10.1111/nph.13635/abstract

The nutrients in tomatoes, mostly carotenoids, are synthesized in chloroplast. The identified regulators functioning in the development of chloroplast in tomatoes are CUL4-DDB1-DET1CRL4protein complex and GLK2 transcription factor. According to the recent studies of the research group, CUL4, DDB1 and DET1 could result in a retardation of SlGLK2 degradation by the 26S proteasome.

These findings are relevant to the potential of nutrient accumulation in tomato fruit by mediating the plastid level and contribute to a deeper understanding of an important regula-tory loop, linking protein turnover to gene regulation.

This paper was equally contributed by Tang Xiaofeng, Miaomin and Niu Xiangli from School of Biotechnology and Food Engineering, with Liu Yongsheng as the author for correspondence.

Writer: Zhou Jianyu

Editor: Guan Qian